Abstract The development of granulomas with central necrosis harboring Mycobacterium tuberculosis (Mtb) is the hallmark of human tuberculosis (TB).New anti-TB therapies need to effectively penetrate the cellular and necrotic compartments of these lesions and reach sufficient concentrations to eliminate Mtb.BTZ-043 is a novel antibiotic showing good
The protein kinase Mec1 (ATR ortholog) and its partner Ddc2 (ATRIP Silicone Moulds ortholog) play a key role in DNA damage checkpoint responses in budding yeast.Previous studies have established the model in which Ddc1, a subunit of the checkpoint clamp, and Dpb11, related to TopBP1, activate Mec1 directly and control DNA damage checkpoint response
In this paper, we present techniques for automatically classifying players and tracking ball movements in basketball game Cabinet Bench video clips under poor conditions, where the camera angle dynamically shifts and changes.In the core of our system lies Yolo, a realtime object detection system.Given the ground truth boxes collected by our data sp
Background: Complaints of ethical and professional misconduct are lodged and processed by the Health Professions Council of South Africa (HPCSA) in accordance with their legal mandate.Objectives: This study describes the nature and frequency of transgressions by physiotherapists as concluded by the HPCSA for the period from 2010 to 2020.Method: A t